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Early stage mouse embryos
Oleksandr Petrenko comment 0 Comments

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Early stage mouse embryos at the blastomere stage are visualized in this photo. When embryos were presented as two blastomeres, researchers introduced two different color fluorescent proteins inside each one and, according to the color of the daughter blastomeres, it is possible to see from which maternal cell they did originate.

Technique: confocal microscopy;
Authors: G. Recher, M. Goolam, M. Zernicka-Goetz, University of Cambridge;
Source: Nikon’s Small World, 2016 Microphotography Competition.

Details about the technique (with protocol):
M. Zernicka-Goetz, J. Pines “Use of Green Fluorescent Protein in Mouse Embryos”
https://www.sciencedirect.com/science/article/pii/S1046202301911570?via%3Dihub

confocal microscopy embryology embryology confocal microscopy